Development Of Atopic Asthma
Atopic disease occurs when the immune system is dysregulated, resulting in allergic inflammation. Various internal and external factors determine the dysregulation and the development of an atopic disease.
In the first few years of life when the immune system is just developing, you are particularly susceptible to being directed towards the development of an atopic disease. However, this isn’t just relevant to children, given that adults can also manifest atopic disease after a change in environment or chronic stress for example.
This is where the hygiene hypothesis stems from, which suggests that a more hygienic environment and fewer infections may be an important reason why there is an increase in atopic disease. According to this theory, too much hygiene or early avoidance of possible things that can cause an allergic reaction increase risks of atopic disease. Why? Because you actually require the exposure to an allergen in order for your immune system to develop properly. Of course, there is always further understanding required to fully comprehend the ins and outs of the development of atopic conditions like asthma.