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The Root Causes Of Cancer

Written by

Deborah Freudenmann BHSc

The incidence and mortality of cancer is rising across the world, rapidly. Before I jump into some shocking statistics remember that you have the power to cause disease and prevent it based on your daily choices. Every choice has an action and reaction.

Worldwide, an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths occurred in 2020. Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer, with an estimated 2.3 million new cases (11.7%), followed by lung (11.4%), colorectal (10.0 %), prostate (7.3%), and stomach (5.6%) cancers. These percentages simply keep going up! The global cancer burden is expected to be 28.4 million cases in 2040, a 47% rise from 2020. I don’t know about you… but these numbers and ever increasing percentages are something that can’t be ignored.

The more disease goes rampant the more vigilant we should be with our prevention measures. Your efforts to build a “healthy life” are truly critical for prevention and control of cancer.

Cancer-fighting mechanisms

Your body was created to fight cancer. You have built-in systems and mechanisms that can fight the development of cancer if supported. Pretty amazing if you ask me.

However, these protective mechanisms have turned out to be inefficient against the ever-increasing number of toxic products, in the forms of chemicals in foods, pollutants in the air, and radiation, we are exposed to on a daily basis. These toxins, coupled with our unhealthy habits and sedentary lifestyle, have further driven the incidence of cancer.

Fortunately, we have plenty of information on what to avoid, how to fix what’s broken and how to thrive in this world. It requires self-empowerment so that you can support your system.

As per usual, cancer is never a short topic and it shouldn’t be. Cancer is a multifaceted disease with many different causes at play.

In this blog post we will discuss the dysfunction in energy metabolism, failure in cell death, how cancer is a systemic disease, with nutritional deficiencies, infections, immune dysregulation and finally how it thrives in a toxic home! 

Cancer is a disease of energy metabolism

Cancer is basically a metabolic disorder that occurs due to the disturbances in energy production occurring when respiration is exchanged by fermentation.

The instability observed in cancer cells is also recognized as a phenomenon of initial disturbances in the metabolism of cellular energy.

These findings suggest that the impairment of the cellular energy metabolism could be the defining characteristic of most cancers. Moreover, the failure of the immune system to support apoptosis and other anti-cancer mechanisms also plays a role in the development of cancer.

Hence, there is a need to adopt ways to support mitochondrial energy with healthy strategies.

Role of mitochondria:
  • Energy regulation, production of ATP
  • Involved in the maintenance of intracellular calcium levels and buffering
  • Regulates cell numbers and defends against unwanted or dangerous cells by triggering programmed cell death (apoptosis)
  • Signalling between the energy powerhouses themselves is controlled via the production of Reactive Oxygen Species (ROS)
  • Mitochondria are critical for signalling major innate immune pathways and immune cell activation
  • Increasing oxygenation
  • Getting sufficient sleep so that mitochondrion can repair themselves
  • Excellent nutrition in respect to micronutrients.
  • Addressing poor digestive function (Leaky gut, dysbiosis)\
  • Protection of mitochondrial function by Nrf2, increasing reduced glutathione production, increasing mitochondrial antioxidants.
  • Stabilising blood sugar levels
  • Identifying allergies, intolerances and food sensitivities
  • Detoxifying to unload heavy metals, pesticides, drugs, (alcohol, tobacco etc) and volatile organic compounds, all of which negatively influence mitochondrial function.
  • Reducing Stress
  • Balancing hormones
  • Krebs cycle – B1, B2, B3, B5, Fe, Mg, Mn and lipoic acid (all of the B vitamins are necessary for mitochondrial function)
  • CoQ10 (Ubiquinol)- Coenzyme Q10 supports mitochondrial energy production in the electron transport chain by carrying electrons from cytochrome to cytochrome in order for ATP to be produced in the mitochondria. Without CoQ10, there is no electron transfer
  • Alpha-Lipoic acid– Alpha-Lipoic Acid (ALA) is a mitochondrial fatty acid that is highly involved in energy metabolism. It is a potent anti-oxidant compound and works with mitochondria and the body’s natural anti-oxidant defenses.
  • Ozone– Ozone is a powerful mitochondrial stimulant. The fundamental underlying cause behind all degenerative disease from diabetes to heart disease to cancer is decreased mitochondrial energy production. Ozone can often correct this problem. Ozone also increases antioxidant protection by activating Nrf2 more than any other therapy. Under conditions of stress or growth factor stimulation, activation of Nrf2 counteracts the increased reactive oxygen species production in mitochondria. Any Nrf2 activator, was found to promote mitophagy, thereby contributing to the overall mitochondrial homeostasis.
  • Acetyl-L-Carnitine– Acetyl-L-Carnitine is well-known for its ability to protect the mitochondria. Acetyl-L-carnitine (ALC) is derived from the acetylation of carnitine in the mitochondria. Carnitine acetylation helps eliminate oxidative products from the body.
  • Melatonin– Melatonin is a potent antioxidant protecting mitochondria, which are exposed to abundant free radicals. It also increases reduced glutathione, SOD and GPx.
  • Resveratrol– Resveratrol is a naturally occurring polyphenol found in more than 70 species of plants, including grapes, cranberries and peanuts, which was shown to confer diverse physiological effects such as cancer protection, microvascular protection, neuroprotection, cardioprotection, antidiabetic protection and mitochondrial function support.
  • NAC – N-Acetyl Cysteine (NAC) is the precursor for the powerful antioxidant glutathione, has also been effective in treating mitochondrial dysfunction.

Carcinogenesis as a failure of apoptosis

Apoptosis is the process of programmed cell death. Carcinogenesis occurs due to the failure of apoptosis which allows cancer cells to multiply! 

Therefore, regulating the oxidant state and maintaining mitochondrial function with specific antioxidants actually shifts tumour killing to cell death (apoptotic) mechanisms.
Primary and metastatic tumours thrive in areas of the body where the average pO2 (Oxygen pressure) is lower than normal tissues. The average pO2 in tumours is roughly 2-10 mm Hg versus 40-45 mm Hg in normal cells. In these low oxygen conditions, the host is unable to mount a reaction for re-establishing physiological levels.

Adopting strategies to support apoptosis could restore the body’s cancer-fighting potential and help to prevent cancerous and precancerous changes in the healthy tissues.

Research has demonstrated that ozone has the ability of being an anti-metastatic agent, as well as preventative approach.

1. Oxygenation and improved oxygen metabolism

Regulation of oxygen metabolism and oxygenation in the use of aerobic pathway for the production of energy. Cancer is anaerobic (no oxygen required to survive) and therefore uses lactic acidosis. Ozone improves tumour oxygenation by significantly and constantly increasing oxygen availability and microcirculation which may slow down tumour growth and inhibit metastasis. 

2. Increases antioxidants and reduces oxidative stress

The mild oxidative stress produced by ozone therapy stimulates the increase of cellular antioxidant enzymes (Nrf2 activator) capable of inhibiting chronic oxidative stress. In cancer, a persistent oxidative stress has been noted as a factor favouring the progression of invasion and metastasis and therefore important to counteract. The fact that cancer cells live better in a hypoxic environment may imply that they don’t have an antioxidant system to get rid of free radicals. Therefore, ozone could exert important cytotoxic effects on tumour cells if they have a poor defense system. Furthermore, ozone accelerates the citric acid cycle and stimulates mitochondrial activity usually impaired in cancer patients.

3. Modulates and activates the immune system

Ozone modulates the immune system making possible the recovery of the immunological response against the tumour cells. Through the action of hydrogen peroxide, it acts as a mild inducer of cytokines in white blood cells and therefore by releasing cytokines in lymphoid microenvironments (lymph nodes, thymus, tonsils, spleen etc.) it activates the immune system usually suppressed by tumour growth.

Systemic ozone applications are hyperbaric ozone multipass or major autohemotherapy which you can get from an ozone doctor. If these two options are not available then rectal ozone insufflations will do the same just slightly slower. 

Interested in ozone therapy? CLICK HERE

Cancer as a systemic disease

Though cancer is usually “diagnosed” in one organ or a part of the body, it is considered a systemic disease.

The development of cancer is linked to chronic inflammation and oxidative stress. Emotional stress and anxiety are also implicated as the factors responsible for triggering the development of cancer.

Many root causes of cancer tend to affect the body as a whole and are not limited to any one organ or system. Therefore it is important to provide systemic support to the body in order to reduce the risk of cancer. Cancer cannot develop in a body that is functioning optimally.

Reducing inflammation – Almost every modern disease today can be linked to chronic inflammation. If your body is continually exposed to stimuli that triggers an inflammatory response your immune system is always on red alert. Addressing the triggers of inflammation and leading an anti-inflammatory lifestyle can not only increase your lifespan, slowing aging, but also decrease your risk of chronic disease.

Eating a nutrient dense diet – Sugar feeds cancer! Cancer cells transport large amounts of glucose in order to produce anabolic precursors and energy within the inhospitable environment of a tumour. Cancer cells are largely dependent on glucose and glycolysis for growth and survival due to abnormalities in the number and function of their mitochondria. Thus, reducing the intake of simple carbohydrates can beneficially impact cancer growth and development.

Improving gut function – The microbes in our gut play crucial roles in your digestion, immunity, metabolism and mental health. A balanced microbiome is linked to a healthy immune system, nervous system, endocrine system, hepatic system, cardiovascular system and almost every other system we have in the body!

In addition to the above, systemic treatments such as PEMF therapy, hyperthermia, lymphatic support, detoxification, nutritional treatment… are all beneficial in supporting how well your overall system is functioning.

Nutritional deficiencies cause whole body dysfunction

Nutritional deficiencies can reduce the body’s ability to functional optimally in almost all systems of the body. Deficiencies can contribute to chronic widespread inflammation in the body, thereby setting the stage for the initiation of cancerous changes in the healthy tissues.
This marks the need to consume a nutritious and balanced diet that comprises all the essential vitamins and minerals as well as a good amount of proteins and healthy fats to support the natural healing of diseases areas. However, often diet isn’t enough and supplementation is necessary. 

Some suggestions

Malnourished patients have a greater susceptibility to infectious complications along with delayed wound healing, which, in combination with their diseased state, significantly increases post-operative morbidity and mortality.

  • Ensuring hydration, drinking at least 2-3 l of water per day. Dehydration also impairs the supply of oxygen and nutrients to the wound or affected area.
  • Essential amino acids including arginine and sulphur-containing amino acids (taurine, methionine, cysteine), are required for optimal wound healing and collagen deposition.
  • Iron, vitamin B12, and folate will help support red blood cell synthesis.
  • Support the immune system with anti-inflammatory healing foods and nutrients. 
  • Ensure proper digestion is maintained by supplementation with digestive enzymes (bromelain, trypsin and pancreatin).

Cancer as an infection due to immune dysregulation

Infections can raise the risk of cancer in different ways. Some viruses are known to affect the genes inside the cells directly thus interfering with their growth. These viruses may insert their own genes into the healthy cells, causing them to grow out of control.

Similarly, some infections can cause chronic inflammation while some are known to suppress the activities of the immune system. Thus, infections can make patients more vulnerable to developing cancer.

Hyperthermia/Sauna and Pathogens

Hyperthermia is probably the most effective treatment against a number of viral and bacterial infections. The body naturally generates a fever in the face of infection as healing mechanism. The positive effects of natural fever and therapeutic hyperthermia treatments are huge.

These effects are also in part, due to heat shock proteins. Heat shock proteins are produced as a result of fever, inflammation and oxidant injury. These proteins help support the immune system to flag pathogens, mutated cells and reduce damage to healthy tissue. The healthy production of heat shock proteins has been indicated in a wide range of conditions including Alzheimer’s, cancer and infections.

Aside from the heat shock proteins, viral and bacterial pathogens are unable to replicated in the increased heat environment and can be rapidly dealt with by the immune system.

Hyperthermia treatments have been found to be beneficial in many patients to restore immune function, support chronic disease and help eradicate viral/bacterial infections.

Cancer thrives in a toxic environment

Cancer cells have learnt to survive and thrive in toxic environments such as heavy metals. These heavy metals may be; carcinogenic (cause cancer), disrupt the nervous system (brain function), affect the microbiome (gut bacterial balance) and commonly affect the endocrine system (hormones).

There are specifically toxins that accumulate in cancer cells. Research has shown that cancer cells store up to 40000 times higher amounts of toxins than healthy cells. Cancer cells often partner up with toxins and pathogens such as heavy metals, mould, bacteria and viruses.

We are not only exposed to one toxin at a time but to a cocktail of heavy metals and other toxicants in our environment. It has been demonstrated that a singular toxin might not cause major damage but the accumulation / compound of toxins increases its toxicity manifold and is the contributing factor to many chronic disease states.

Regular detoxification would help to stimulate the elimination of heavy metals like mercury and lead and other toxins from the body. It would also help cleanse the blood and rejuvenate the organs and tissues thus restoring the body’s disease-fighting potential.

Liver Support – Our liver is the organ most important to the processing and breakdown of toxins and metabolic wastes in the body. Taking specific liver supportive nutrients and eating plenty of cruciferous veggies like cabbage, kale, Brussels sprouts, etc.

Dietary Support – Ensure that you include soluble and insoluble fibre, and resistant starch in your daily diet. These are important for the health of the gut generally and for promoting daily elimination of wastes via the bowels. One to three bowel movements a day is ideal.

Hydration – I’ve already mentioned it, but I’ll mention it again… consume at least 1.5-2 L of filtered water as part of your daily routine. Optimal fluid intake is essential as kidneys are responsible for the elimination of metabolic and ingested wastes and toxins.

Pulse electromagnetic field frequency (PEMF) therapy can also help facilitate heavy metal detoxification.

Sauna therapy to detox and reduce inflammation. One of the leading markers of systemic inflammation is C-reactive protein. An acute phase reactant generated by the liver as it works to detoxify the blood, levels of CRP increase rapidly in response to infection, inflammation, and trauma.

Regular physical activity is important for promoting good circulation of blood and lymphatic fluid throughout the body. Rebounding, trampolining, skipping and sauna sessions are effective ways of improving and maintaining these functions.


Identifying the root cause of cancer is essential for reducing the risk of this disease. Cancer is a multifaceted disease and there are countless causes found to be a trigger for development. Prevention as always is the best way to avoid cancerous development in the first place. However, removing as many “causes” to cancer as possible no matter your stage or state of health will have a positive outcome. Adopting healthy strategies to fight carcinogenic agents and supporting the body’s own cancer-fighting mechanisms are the keys to protecting yourself against this disease. If you are interested get in contact with us as we offer a very comprehensive course that not only helps to understand all causes of disease but also ways to address them.

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  • 2 Responses

    1. Dear Deborah,
      Your Cancer blog was an excellent Reminder of all the components of ways of
      remaining cancer free. I especially appreciate your reference to Oxygenation.
      (The Warburg effect? Good old Felix Warburg). Thanks!
      Helen L. (sent from Staten Island, NY, USA)

    2. Greetings,

      Very good information Thank you. I would also like to point that Viruses 🦠 with toxic heavy metal contribute to the development of cancer cells . Please read any of the books by “Medical Medium” New York Time #1 best seller by Anthony William
      Much love 💕

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